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Autologous Adipose-Derived Stem Cell Therapy



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We offer stem cell therapy using adipose tissue-derived

stem cells. In this treatment, a small amount of your own abdominal fat is collected and cultured to obtain stem cells, which are then administered through methods such as intravenous infusion or local injections.

The administered stem cells circulate through the body and target areas in need of repair, facilitating tissue regeneration and repair.

It is a form of regenerative medicine aimed at repairing and rejuvenating damaged or injured tissues.


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Stem cells are a general term tor rare cells with unique abilities, such as self-replication and multi-potency. They play a role in repairing dam­ aged tissues within the body and replenishing cells in aging tissues.

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The ability to differentiate into various cells that make up the body, such as bones, muscles, skin, hair follicles, blood

vessels. nerves, liver, pancreas, and more.

Theability to replicate cells with the exact same capabilities

asonesdt:

Multi-potency

Self-replication

ability

Stem cells are being researched for various medical applications, including the treatment of rare diseases, health enhancement, and an­ ti-aging medicine.

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What are adipose tissue-derived stem cells?

Adipose tissue-derived stem cells are stem cells found in very small quantities within adipose tissue. These are entirely different cells from the fat cells that make up subcutaneous fat.

These adipose tissue-derived stem cells, which are a type of mesenchymal stem cell naturally present in the body and referred to as mesenchymal stem cells, possess highly unique properties.

Extensive research has shown that they have a high therapeutic potential for various diseases, and they are promising stem cells with the potential to contribute significantly to regenerative medicine.

The ability to regulate and restore normalcy by addressing immune or inflammatory abnormalities (immunomodulatory action).

The ability to migrate to damaged areas of tissues (homing effect).

The ability to secrete various functional substances and influence neighboring cells (paracrine effect). It is possible to isolate stem cells from a small amount of subcutaneous fat.

It is possible to obtain a larger number of stem cells compared to other types of stem cells.

It requires no genetic manipulation, and the risk of cancer development is extremely low.


Stem Cell Therapy Procedure

This treatment involves harvesting cells from your own abdominal area, isolating and culturing stem cells from them, and then reintroducing them into your body.

01. Stem Cell Therapy Procedure

A small amount ofadipose tissue is collected from the subcutaneous fat in the abdomen. Specialized medical professionals perform this procedure through a very small incision in the lower abdomen, leaving minimal scarring.


02. Culturing of stem cells

At the Cell Processing Facility (CPF), adipose tissue-derived stem cells are isolated and cultured under strict supervision. The culturing period, which ensures an adequate number of cells for the initial treatment, is approximately 5 weeks. Stem cells are cryopreserved, allowing for subsequent administrations to take place with a culturing period of4 weeks.

03.Administration of stem cells

Depending on the treatment objectives, adipose tissue-derived stem cells are administered via intravenous infusion or local injections. Specialized physicians in regenerativt: medicint:, following the Regent:rative Medicint: Provision Plan, perform the procedure with strict satety protocols.


The Key Features of Our Autologous Adipose-DerivedStem Cell Therapy at Our Clinic


Our clinic follows a treatment plan where the cells are cultured and administered within 48 hours.


We administer approximately 100 million autologous adipose-derived stem cells in their fresh state, without freezing, resulting in significantly enhanced effects of cytokines, growth factors, and exosomes.

Very few clinics in Japan administer live stem cells.



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Case Reports of Treatment Using Adipose Tissue-Derived Stem Cells


The effectiveness of adipose tissue-derived stem cells has been reported in various diseases in both domestic and international basic and clinical research.At our clinic, we have obtained the Ministry of Health, Labour and Welfare's certification as a Type 2 provider for autologous adipose-derived stem cell therapy.


Cerebral lnfa.rcti, m (Stn ,ke)

Peripheral Artery Disease

Brain C, ,nrusii ,n

Diabetes

Spinal Cord Injury

Chn mic Kidney Disease

Multiple Sclerosis

Lil'er Disease (Pneum, mia, Cirrh, ,sis, Hepatic Dis, ,rders, etc.)

Hypoxic lschemic Encephalopathy

Primary Biliary Cirrhosis

Parkinson's Disease

Emphysema

Alzheimer's Type Dementia

Pulmonary Fibrosis

Amy, ,rn ,phic Lateral Sden ,sis (ALS)

Chronic Obstructive Pulmonary Disease (COPD)

P,,Ii,, (P, ,Ii, ,myelitis)

Autoimmune Diseases (Rheumatoid Arthritis, Systemic Lupus Erythcmatosus, etc.)

Peripheral Nerve Damage

Graft-Versus-I-I, ,st Disease (GVHD)

Clm mic Pain

Men< ,pausal Sympt, ,ms in \ V, ,men

Knee Oste, ,arthritis

Male Mern ,pausal Sympt, ,ms

Tend, ,n Injury

Benign Pn ,static HyperpiJsia (Enlarged Pn ,state)

Arthritis

Erectile Dysfuncti, ,n

Refract, ,ry Fractures

Urinary Inc, mtinence

Py, ,derma Gangrern ,sum

B, me Deficiency

At, ,pie Dermatitis


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Acne Scars

Periodontal Disease

Vitilig,,

Post-Breast Cancer Surgery (Breast Reconstruction)

Andn ,genetic Al, ,pecia (Male Pattern Baldness)

Post-Breast Augmentation

Other Types, ,f Al, ,pecia

Anti-Aging Medicine (Rejuvenation of Skin, Blood \'essels, etc.)

Myocardial Infarction (Heart Attack), Angina Pectoris (lschemic Chest Pain)

CO\IID-19 (Coronavirus Disease)

Atherosderosis

P, ,st-COVID-19 Svndn ,me



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Our Clinic's Process


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Please make a reservation one month in advance.

For Al Human Health Check options, we kindly request reservations to be made one and a half months in advance.


image We will confirm your reservation once payment has been received. image Please send us the medical questionnaire and the results of your blood tests. image Please arrive at the clinic 15 minutes prior to your appointment on the day.

image The adipose tissue harvesting procedure takes approximately 30 to 60 minutes.


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After adipose tissue harvesting, we kindly ask you to take a short break, and then we will discuss the schedule for stem cell administration.


*The Al Diagnostic Human Health Check will be conducted at the Hanwa Intelligent Medical Center.


*The Al Diagnostic Human Health Check is not available on Tuesdays, Saturdays, and Sundays.


The current acceptance schedule



Mon

Tue

Wed

Thu

Fri

Sat

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Cell C.,llecti, ,n 10 pe,,pie per day


Cell C.,llecti, m 10 pe,,pie per day


Cell Cullcctiun 10 people per day

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Health Check

n pe,,pie per day


Health Check 6 peuple per day

Health Check 6 pe,,pie per day

Health Check 6 pe, ,pie per day


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